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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Recombinant human CD14 protein, C-His (HEK293) (bs-43686P)  
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產(chǎn)品編號(hào) bs-43686P
英文名稱 Recombinant human CD14 protein, C-His (HEK293)
中文名稱 重組人內(nèi)毒素受體蛋白
別    名 CD14 antigen; CD14 molecule; Lipopolysaccharide receptor; LPSR; Monocyte Differentiation Antigen 14; Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein; CD14_HUMAN; Myeloid cell-specific leucine-rich glycoprotein.  
理論分子量 37kDa
性    狀 Lyophilized or Liquid
濃    度 >0.5mg/ml
純    度 >90% as determined by SDS-PAGE
緩 沖 液 PBS (pH=7.4)
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]

SWISS:
P08571

Gene ID:
929

CD14又稱內(nèi)毒素受體,屬細(xì)胞表面糖蛋白家族成員之一。在機(jī)體免疫、防御系統(tǒng)引起的一系列反應(yīng)中介導(dǎo)細(xì)胞識(shí)別LPS并引起細(xì)胞酪氨酸磷酸化、核因子NF-κB轉(zhuǎn)位、觸發(fā)細(xì)胞因子釋放和氧自由基產(chǎn)生。CD14在細(xì)胞因子產(chǎn)生的調(diào)控方面起重要作用,因而對(duì)于CD14結(jié)構(gòu)、功能及其臨床意義的研究日益受到重視。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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