產(chǎn)品編號(hào) | bs-43686P |
英文名稱 | Recombinant human CD14 protein, C-His (HEK293) |
中文名稱 | 重組人內(nèi)毒素受體蛋白 |
別 名 | CD14 antigen; CD14 molecule; Lipopolysaccharide receptor; LPSR; Monocyte Differentiation Antigen 14; Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein; CD14_HUMAN; Myeloid cell-specific leucine-rich glycoprotein. |
理論分子量 | 37kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5mg/ml |
純 度 | >90% as determined by SDS-PAGE |
緩 沖 液 | PBS (pH=7.4) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010] SWISS: P08571 Gene ID: 929 CD14又稱內(nèi)毒素受體,屬細(xì)胞表面糖蛋白家族成員之一。在機(jī)體免疫、防御系統(tǒng)引起的一系列反應(yīng)中介導(dǎo)細(xì)胞識(shí)別LPS并引起細(xì)胞酪氨酸磷酸化、核因子NF-κB轉(zhuǎn)位、觸發(fā)細(xì)胞因子釋放和氧自由基產(chǎn)生。CD14在細(xì)胞因子產(chǎn)生的調(diào)控方面起重要作用,因而對(duì)于CD14結(jié)構(gòu)、功能及其臨床意義的研究日益受到重視。 |
產(chǎn)品圖片 | |