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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Recombinant human CD146 protein, C-His (bs-43688P)  
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產(chǎn)品編號 bs-43688P
英文名稱 Recombinant human CD146 protein, C-His
中文名稱 重組人黑色素瘤細胞粘附分子CD146蛋白
別    名 A32 antigen; CD 146; CD146 antigen; Cell surface glycoprotein MUC18; Cell surface glycoprotein P1H12; MCAM; Melanoma adhesion molecule; Melanoma associated antigen A32; Melanoma associated antigen MUC18; Melanoma associated glycoprotein MUC18; Melanoma ce  
理論分子量 61.7kDa
性    狀 Liquid
濃    度 >0.5mg/ml
純    度 >90% as determined by SDS-PAGE
緩 沖 液 PBS (pH=7.4)
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 MCAM (MUC18 antigen, CD146), a member of the immuoglobulin superfamily, is an intrinsic membrane glycoprotein of 110-120 kDa found on the surface of endothelial cells, bone marrow fibroblasts and various melanomas. MCAM (Melanoma adhesion molecule) has been used as a marker of tumor progression in human melanoma because expression in those tumors correlates strongly with poor prognosis and the development of metastic disease. In addition, a number of human T, B and myeloid leukemic cell lines seem to express MCAM. The close structural relationship with N-CAM and related molecules suggests that MCAM may be also a developmentally regulated cell adhesion.

SWISS:
P43121

Gene ID:
4162

CD146分子主要是選擇性的在腫瘤血管內(nèi)皮細胞中表達較高。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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