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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Recombinant human MARCH8 protein (bs-42425P)  
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說明書: 100ug  500ug  
100ug/2980.00元
500ug/9500.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-42425P
英文名稱 Recombinant human MARCH8 protein
中文名稱 重組人膜相關(guān)環(huán)指蛋白8
別    名 c MIR; c-MIR; Cellular modulator of immune recognition; E3 ubiquitin protein ligase MARCH8; E3 ubiquitin-protein ligase MARCH8; MARCH 8; MARCH VIII; MARCH-VIII; MARCH8; MARH8_HUMAN; Membrane associated RING CH protein VIII; Membrane associated ring finger  
理論分子量 45.9kDa
性    狀 Liquid
濃    度 >1mg/ml
純    度 >90% as determined by SDS-PAGE
緩 沖 液 50mM Tris-Hcl (pH=8.0) with 10mM GSH and 0.5mM PMSF
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. MARCH8 (membrane-associated ring finger (C3HC4) 8), also known as MIR or RNF178 (RING finger protein 178), is a 291 amino acid multi-pass membrane protein that localizes to vesicle membranes and contains one RING-CH-type zinc finger. Expressed in a variety of tissues, including immature dendritic cells, MARCH8 functions as an E3 ubiquitin ligase that is thought to regulate immune responses by promoting the ubiquitination and subsequent degradation of target proteins, such as B7-2 and CD71.

SWISS:
Q5T0T0

Gene ID:
220972

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