產(chǎn)品編號 | bs-42445P |
英文名稱 | Recombinant human COL2A1 protein, GST& His |
中文名稱 | 重組人Ⅱ型膠原α1蛋白 |
別 名 | Collagen II alpha 1; COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1(II); type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; Chondrocalcin; COL11A3; Collagen alpha 1(II) chain precurs |
理論分子量 | 36.3kDa |
性 狀 | Liquid |
濃 度 | >1mg/ml |
純 度 | >90% as determined by SDS-PAGE |
緩 沖 液 | 50mM Tris-Hcl (pH=9.0) with 5mM GSH and 0.5mM PMSF |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008] SWISS: P02458 Gene ID: 1280 Ⅱ型膠原是軟骨基質(zhì)中的一種結(jié)構(gòu)蛋白;Ⅱ型膠原不與Ⅰ、Ⅲ、Ⅳ、Ⅴ、Ⅵ膠原以及其它血清蛋白或非膠原性細胞外相關(guān)蛋白起交叉反應(yīng)。II型膠原最先發(fā)現(xiàn)于軟骨基質(zhì)中,在眼睛中也有少量存在。組成II型膠原的纖維較I型膠原更纖細。該抗體可以特異性識別II型膠原,與其他類型的膠原無交叉反應(yīng),抗II型膠原抗體-主要用于Ⅱ型膠原分布及變態(tài)反應(yīng)方面及良/惡性腫瘤的細胞外基質(zhì)方面的研究。 |
產(chǎn)品圖片 | |
1、抗體溶解方法 | |
2、抗體修復(fù)方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關(guān)于肽鏈的設(shè)計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |