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Recombinant human COL2A1 protein, GST& His (bs-42445P)  
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產(chǎn)品編號 bs-42445P
英文名稱 Recombinant human COL2A1 protein, GST& His
中文名稱 重組人Ⅱ型膠原α1蛋白
別    名 Collagen II alpha 1; COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1(II); type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; Chondrocalcin; COL11A3; Collagen alpha 1(II) chain precurs  
理論分子量 36.3kDa
性    狀 Liquid
濃    度 >1mg/ml
純    度 >90% as determined by SDS-PAGE
緩 沖 液 50mM Tris-Hcl (pH=9.0) with 5mM GSH and 0.5mM PMSF
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]

SWISS:
P02458

Gene ID:
1280

Ⅱ型膠原是軟骨基質(zhì)中的一種結(jié)構(gòu)蛋白;Ⅱ型膠原不與Ⅰ、Ⅲ、Ⅳ、Ⅴ、Ⅵ膠原以及其它血清蛋白或非膠原性細胞外相關(guān)蛋白起交叉反應(yīng)。II型膠原最先發(fā)現(xiàn)于軟骨基質(zhì)中,在眼睛中也有少量存在。組成II型膠原的纖維較I型膠原更纖細。該抗體可以特異性識別II型膠原,與其他類型的膠原無交叉反應(yīng),抗II型膠原抗體-主要用于Ⅱ型膠原分布及變態(tài)反應(yīng)方面及良/惡性腫瘤的細胞外基質(zhì)方面的研究。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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