產(chǎn)品編號(hào) | bs-42449P |
英文名稱(chēng) | Recombinant human CXADR Protein, N-His |
中文名稱(chēng) | 重組人柯薩奇病毒蛋白受體B |
別 名 | 46 kD coxsackievirus and adenovirus receptor CAR protein; 46 kD coxsackievirus and adenovirus receptor protein; CAR; CAR4/6; Coxsackie virus and adenovirus receptor; Coxsackie virus B receptor; Coxsackievirus and adenovirus receptor; Coxsackievirus B aden |
理論分子量 | 27.7kDa |
性 狀 | Liquid |
濃 度 | >1mg/ml |
純 度 | >90% as determined by SDS-PAGE |
緩 沖 液 | 20mM Tris-Hcl (pH=8.0) with 8M Urea |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Coxsackie and adenovirus receptor (CAR), also known as CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity. It is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.It is proposed to function as a homophilic cell adhesion molecule and recruits MPDZ to intercellular contact sites. CAR is probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN) through adhesive interactions with AMICA1/JAML located in the plasma membrane of PMN. SWISS: P78310 Gene ID: 1525 |
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