產品編號 | bs-3876R |
英文名稱 | Rabbit Anti-APOA4 antibody |
中文名稱 | 載脂蛋白A4抗體 |
別 名 | Apo AIV; APOA 4; Apolipoprotein A IV; MGC142154; MGC142156. |
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Specific References (1) | bs-3876R has been referenced in 1 publications.
[IF=5.008] Wang et al. Proteome-based identification of apolipoprotein A-IV as an early diagnostic biomarker in liver fibrosis. (2017) Oncotarge. 8:88951-88964 WB ; Rat.
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研究領域 | 心血管 免疫學 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Human,Rat (predicted: Mouse,Rabbit,Dog) |
產品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 44kDa |
細胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human APOA4: 325-375/396 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產品介紹 |
APOA4 (apolipoprotein A-IV) is a component of HDL and chylomicrons. Its primary site of synthesis is the intestine, in association with lymph chylomicron particles. Although its precise function is not known, APOA4 is a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. In rodents, Apo A-IV inhibits gastric emptying and serves as a satiety factor whose synthesis and secretion are increased by the ingestion of dietary fat. It also possesses anti-inflammatory and antiatherogenic properties Function: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. Subcellular Location: Secreted. Tissue Specificity: Synthesized primarily in the intestine and secreted in plasma. Post-translational modifications: Phosphorylation sites are present in the extracellular medium. Similarity: Belongs to the apolipoprotein A1/A4/E family. SWISS: P06727 Gene ID: 337 Database links: Entrez Gene: 337 Human Omim: 107690 Human SwissProt: P06727 Human Unigene: 1247 Human |
產品圖片 | |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |