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Rabbit Anti-TNFAIP5  antibody (bs-5783R)  
~~~促銷,代碼KT202502A~~~
~~~促銷,代碼KT202502B~~~
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產品編號 bs-5783R
英文名稱 Rabbit Anti-TNFAIP5  antibody
中文名稱 腫瘤壞死因子α誘導蛋白5抗體
別    名 Pentaxin 3; Pentaxin3; Pentaxin-3; Pentaxin-related protein PTX3; Pentraxin-related gene; Pentraxin-related gene, rapidly induced by IL-1 beta; Pentraxin-related protein PTX3; PTX3; PTX3_HUMAN; TNF alpha-induced protein 5; TNFAIP5; TSG-14; TSG14; Tumor necrosis factor alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; Tumor necrosis factor-inducible protein TSG-14.  
Specific References  (3)     |     bs-5783R has been referenced in 3 publications.
[IF=5.12] Sato, Kengo, et al. "Potent Vasoconstrictor Kisspeptin‐10 Induces Atherosclerotic Plaque Progression and Instability: Reversal by its Receptor GPR54 Antagonist." Journal of the American Heart Association 6.4 (2017): e005790.  IHC ;  Mouse.  
[IF=2.06] Liu, Chao, Yao Yao, and Wei Wang. "Pentraxin-3 as a prognostic marker in patients with small-cell lung cancer." Medical Oncology 31.10 (2014): 1-6.  IHC-P ;  Human.  
[IF=0] Watanabe, Rena, et al. "Atheroprotective Effects of Tumor Necrosis Factor–Stimulated Gene-6." JACC: Basic to Translational Science 1.6 (2016): 494-509.  IHC ;  Mouse.  
研究領域 腫瘤  心血管  免疫學  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Rat (predicted: Mouse,Rabbit,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 40kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNFAIP5/Pentraxin 3: 151-250/381 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.

Function:
Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.

Subcellular Location:
Secreted.

Post-translational modifications:
Glycosylated (Probable).

Similarity:
Contains 1 pentaxin domain.

SWISS:
P26022

Gene ID:
5806

Database links:

Entrez Gene: 5806 Human

Entrez Gene: 19288 Mouse

Omim: 602492 Human

SwissProt: P26022 Human

SwissProt: P48759 Mouse

Unigene: 591286 Human

Unigene: 276776 Mouse

Unigene: 442151 Mouse



Pentraxin 3含有381個氨基酸,屬于同源的pentraxin蛋白家族。Pentraxin 3能有效預防巨細胞病毒感染,以及預防隨后曲霉感染。PTX3可與可溶性模式識別受體作用,因此可以抵抗真菌病原體煙曲霉等。PTX3可能有治療基因骨髓移植和類似免疫機能喪失的功能。
產品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (TNFAIP5) Polyclonal Antibody, Unconjugated (bs-5783R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.
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