| 產(chǎn)品編號(hào) | bs-6248R |
| 英文名稱 | Rabbit Anti-IMPAD1 antibody |
| 中文名稱 | 肌醇單磷酸酶IMPA3抗體 |
| 別 名 | IMP 3; IMPA3; IMPase 3; Inositol monophosphatase domain containing protein 1; Myo inositol monophosphatase A3. |
| 研究領(lǐng)域 | 腫瘤 心血管 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IMPAD1: 81-180/359 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. Function: May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation Subcellular Location: Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Post-translational modifications: Contains N-linked glycan resistant to endoglycosydase H. DISEASE: Defects in IMPAD1 are the cause of chondrodysplasia with joint dislocations GPAPP type (CDP-GPAPP) [MIM:614078]. A condition consisting of congenital joint dislocations, chondrodysplasia with short stature, micrognathia and cleft palate, and a distinctive face. Similarity: Belongs to the inositol monophosphatase family. SWISS: Q9NX62 Gene ID: 54928 Database links: Entrez Gene: 54928 Human Entrez Gene: 242291 Mouse Omim: 614010 Human SwissProt: Q9NX62 Human SwissProt: Q80V26 Mouse Unigene: 438689 Human Unigene: 218889 Mouse Unigene: 369779 Mouse Unigene: 65720 Rat |
| 產(chǎn)品圖片 |
Sample:
Muscle(Mouse) (Mouse) Lysate at 40 ug
Primary: Anti-IMPAD1 (bs-6248R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 39 kD
Observed band size: 39 kD
|
