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Recombinant mouse IL21 protein, N-His (bs-42370P)  
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產(chǎn)品編號 bs-42370P
英文名稱 Recombinant mouse IL21 protein, N-His
中文名稱 重組小鼠白介素21蛋白
別    名 Interleukin 21; Interleukin21; IL 21; IL-21; Za11; Interleukin-21; interleukin-21 isoform; IL21_HUMAN.  
理論分子量 16.6kDa
性    狀 Liquid
濃    度 >0.5mg/ml
純    度 >90% as determined by SDS-PAGE
緩 沖 液 PBS (pH=8.0) with 5% Glycerol
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 IL-21 is a typical family I cytokine with broad pleiotropic actions and is primarily produced by T follicular helper cells, Th17, and natural killer T cells in response to antigenic stimulation. Il-21 generally enhances antigen-specific responses of immune cells. It controls the activation, proliferation, differentiation, cytotoxicity, and survival of various target immune cells. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 elicits its effect through binding to IL-21R, which also contains the gamma chain found in other cytokine receptors such as IL-2, IL-4, IL-7, IL-9 and IL-15. IL-21/IL-21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Human IL-21 is a 15.4 kDa protein consisting of 132 amino acid residues.

SWISS:
Q9ES17

Gene ID:
60505

白介素21是多效免疫調(diào)節(jié)活性的細胞因子,與其受體結(jié)合后可以調(diào)節(jié)并促進B細胞、T細胞、NK細胞的增殖、分化并提高NK細胞殺傷活性。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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