| 產(chǎn)品編號(hào) | bs-42355P |
| 英文名稱 | Recombinant human Integrin Alpha V + Beta 3 (CD51+CD61) protein, N-His |
| 中文名稱 | 重組人整合素αVβ3蛋白 |
| 理論分子量 | 31.5kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >0.5mg/ml |
| 純 度 | >90% as determined by SDS-PAGE |
| 緩 沖 液 | 20mM Tris-Hcl (pH=8.0) with 6M Urea and 2mM TCEP |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumour cells. ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. SWISS: P06756 Gene ID: 3685 |
| 產(chǎn)品圖片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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