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Recombinant human Calmodulin 1/2/3 protein, N-His (bs-42432P)  
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產(chǎn)品編號 bs-42432P
英文名稱 Recombinant human Calmodulin 1/2/3 protein, N-His
中文名稱 重組人鈣調(diào)節(jié)素蛋白
別    名 CALM 1; CALM 2; CALM 3; CALM; CALM1; CALM2; CALM3; CALML2; Calmodulin 1; Calmodulin1; CAM 1; CAM 2; CAM 3; CaM; CAM I; CAM1; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; DD132; PHKD; Phosphorylase kinase delta; Phosphorylase kinase delta subunit; Calmodulin1; Ca  
理論分子量 20.4kDa
性    狀 Lyophilized or Liquid
濃    度 >1mg/ml
純    度 >90% as determined by SDS-PAGE
緩 沖 液 50mM Tris-Hcl (pH=7.5) with 0.5mM TCEP
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Calmodulin consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Epithelial Calmodulin is found in the large majority of adenocarcinomas of most sites (50-100% in various studies; as well as neuroendocrine tumours, including small cell carcinoma. Renal cell carcinoma and hepatocellular carcinoma stain in about 30% of the cases. Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin Ca(2+) complex are a number of protein kinases and phosphatases. Calmodulin has four functional calcium binding sites.

SWISS:
P0DP23

Gene ID:
801

鈣離子調(diào)節(jié)素(calmodulin,CaM): 鈣調(diào)蛋白(CaM),是由一條多肽鏈組成的單體蛋白??山Y(jié)合4個Ca2+,胞漿Ca2+濃度≥10-2mmol/L時,Ca2+與CaM結(jié)合,構(gòu)象改變而激活Ca2+ -CaM激酶。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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