產(chǎn)品編號(hào) | bs-42396P |
英文名稱 | Recombinant human GSTP1 protein, N-His |
中文名稱 | 重組人谷胱甘肽硫轉(zhuǎn)移酶pi蛋白 |
別 名 | Glutathione S-Transferase pi; GST-Pi; DFN7; Gst-P1; FAEES3; Fatty Acid Ethyl Ester Synthase III; Glutathione S Transferase Pi; GST3; GSTP1; GST pi; PI; GSTP1_HUMAN. |
理論分子量 | 26.9kDa |
性 狀 | Liquid |
濃 度 | >1mg/ml |
純 度 | >90% as determined by SDS-PAGE |
緩 沖 液 | 20mM Tris-Hcl (pH=8.0) with 150mM NaCL |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008] SWISS: P09211 Gene ID: 2950 GST-Pi是GST家族中的一種主要的同工酶,廣泛存在于全身器官中,尤以肝腎含量高,具有解毒功能。在多種腫瘤中高表達(dá)。目前認(rèn)為是腫瘤細(xì)胞產(chǎn)生耐藥的一種標(biāo)記,與腫瘤的耐藥(阿霉素、順鉑、氮芥、環(huán)磷酰胺和瘤可寧等)有關(guān)。該抗體主要用于細(xì)胞耐藥方面的研究。 |
產(chǎn)品圖片 | |