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Recombinant mouse CD4 protein (HEK293) (bs-43673P)  
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產(chǎn)品編號 bs-43673P
英文名稱 Recombinant mouse CD4 protein (HEK293)
中文名稱 重組小鼠CD4蛋白
別    名 CD4 (L3T4); CD4 antigen (p55); CD4 Antigen ; CD4 molecule; CD4 Receptor; CD4+ Lymphocyte deficiency, included; CD4mut; L3T4; Leu3; Ly-4; Lymphocyte antigen CD4; MGC165891; p55; T Cell Antigen T4 ; T cell antigen T4/LEU3; T cell differentiation antigen L3T  
理論分子量 43.1kDa
性    狀 Lyophilized or Liquid
濃    度 >0.5mg/ml
純    度 >90% as determined by SDS-PAGE
緩 沖 液 PBS (pH=7.4)
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010].

SWISS:
P06332

Gene ID:
12504

此抗體可識別55KDⅠ型單鏈穿膜糖蛋白。 CD4分子是存在于大多數(shù)輔助/誘導T細胞表面的59kDa的糖蛋白。正常淋巴組織中CD4的表達數(shù)量多于CD8,此抗體主要用于標記輔助/誘導T細胞,與CD8單抗聯(lián)合使用對外周血淋巴細胞分型。 CD4抗原是HLA-II類分子和人類免疫缺陷病毒(HIV)-愛滋病的受體,在35-50%外周血淋巴細胞-輔助和誘導T細胞(Th/Ti)和70-80%人胸腺細胞上表達,在人的單核細胞表面也有低密度的表達。 CD4抗原有膜結(jié)合型和可溶性兩種形式。Th/Ti可輔助Ig產(chǎn)生和T細胞毒T
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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