產(chǎn)品編號 | bs-42413P |
英文名稱 | Recombinant mouse CLEC12A protein,N-His |
中文名稱 | 重組小鼠C型凝集素結(jié)構(gòu)域家族12成員A蛋白 |
別 名 | C-type lectin domain family 12 member A; C-type lectin-like molecule 1; CL12A_HUMAN; CLEC12A; CLL-1; DCAL-2; Dendritic cell-associated lectin 2; MICL; Myeloid inhibitory C-type lectin-like receptor. |
理論分子量 | 25.7kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >1mg/ml |
純 度 | >90% as determined by SDS-PAGE |
緩 沖 液 | 20mM Tris-Hcl (pH=8.0) with 8M Urea |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-12A (C-type lectin domain family 12, member A), also known as CLL1, MICL, CLL-1 or DCAL-2, is a 275 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Existing as multiple alternatively spliced isoforms that are expressed in neutrophils, eosinophils, monocytes and dendritic cells, CLEC-12A functions as a cell surface receptor that acts as a negative regulator of granulocyte and monocyte function and, via this activity, modulates signaling cascades. CLEC-12A is highly subject to post-translational glycosylation at its N-terminus and may also exist as a homodimer. SWISS: Q504P2 Gene ID: 232413 |
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