產(chǎn)品編號 | bs-3876R-Gold |
英文名稱 | Rabbit Anti-APOA4/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的載脂蛋白A4抗體 |
別 名 | Apo AIV; APOA 4; Apolipoprotein A IV; MGC142154; MGC142156. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 心血管 免疫學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Rat, (predicted: Mouse, Dog, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 44kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human APOA4 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: APOA4 (apolipoprotein A-IV) is a component of HDL and chylomicrons. Its primary site of synthesis is the intestine, in association with lymph chylomicron particles. Although its precise function is not known, APOA4 is a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. In rodents, Apo A-IV inhibits gastric emptying and serves as a satiety factor whose synthesis and secretion are increased by the ingestion of dietary fat. It also possesses anti-inflammatory and antiatherogenic properties Function: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. Subcellular Location: Secreted. Tissue Specificity: Synthesized primarily in the intestine and secreted in plasma. Post-translational modifications: Phosphorylation sites are present in the extracellular medium. Similarity: Belongs to the apolipoprotein A1/A4/E family. Database links: Entrez Gene: 337 Human Omim: 107690 Human SwissProt: P06727 Human Unigene: 1247 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |